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Ruxolitinib

SKU: orb1307364

Description

Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50=3.3/2.8 nM). It demonstrates antitumor effects by inducing autophagy and apoptosis, making it a valuable tool for in vitro and in vivo research in oncology and immunology.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number941678-49-5
MW306.37
Purity>98%
FormulaC17H18N6
SMILESN#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
TargetKinase
SolubilitySoluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

INCB 018424

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Ruxolitinib (orb1307364)

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Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 100.00
5 mg
$ 100.00
10 mg
$ 110.00
25 mg
$ 140.00
50 mg
$ 160.00
100 mg
$ 200.00
200 mg
$ 300.00
500 mg
$ 480.00
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