(S)-10-Hydroxycamptothecin

SKU: orb1305050

Description

(S)-10-Hydroxycamptothecin (10-HCPT) is a potent topoisomerase I inhibitor used in cancer research. It demonstrates significant antitumor activity in both in vitro cell assays and in vivo models, particularly in studies focused on hepatoma and other solid tumors.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 19685-09-7
• MW: 364.35
• Purity: 99.09% (May vary between batches)
• Formula: C₂₀H₁₆N₂O₅
• SMILES: O=C1N2C(C=3C(C2)=CC=4C(N3)=CC=C(O)C4)=CC5=C1COC(=O)[C@@]5(CC)O
• Target: Apoptosis,Topoisomerase
• Solubility: DMSO:26 mg/mL (71.36 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PCNA, p53, G2/M, Cell-cycle, c-Myc, (S) 10 Hydroxycamptothecin, 10-HCPT, 10-Hydroxycamptothecin, (S)10Hydroxycamptothecin, caspase-1/3r, Bcl-2, Apoptosis, antitumor, arrest, Bax, Topoisomerase, Topo I

Quick Database Links

Gene Symbol

Apoptosis,Topoisomerase