(S)-(-)-Bay-K-8644

SKU: orb1296175

Description

(S)-(-)-Bay K 8644 is a potent and selective L-type calcium channel agonist, activating Ba²⁺ currents with an EC₅₀ of 32 nM. It is widely used in cardiovascular and neurological research to study calcium signaling in vitro and to modulate blood pressure and cardiac function in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 98625-26-4
• MW: 356.3
• Purity: 98.28% (May vary between batches)
• Formula: C₁₆H₁₅F₃N₂O₄
• SMILES: COC(=O)C1=C(C)NC(C)=C([C@H]1c1ccccc1C(F)(F)F)[N+]([O-])=O
• Target: Calcium Channel
• Solubility: DMSO:120 mg/mL (336.79 mM);H2O:< 0.1 mg/mL (insoluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.23 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, L-type calcium channel, CalciumChannel, Bay K 8644, Bay K8644, Bay K-8644, Bay-K 8644, Bay-K8644, Bay-K-8644, Ca channels, Ca2+ channels, Calcium Channel, (S) ( ) Bay K 8644, (S)-(-)-Bay K 8644, (S)()BayK8644

Quick Database Links

Gene Symbol

Calcium Channel