SAG hydrochloride (912545-86-9(free base))

SKU: orb1303058

Description

SAG hydrochloride (CAS 912545-86-9 for the free base) is a potent and cell-permeable Smoothened (SMO) receptor agonist. It is widely used in research to activate the Hedgehog signaling pathway for both in vitro cellular studies and in vivo developmental biology experiments.

Research Area

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2095432-58-7
• MW: 526.52
• Purity: 98.00% (May vary between batches)
• Formula: C₂₈H₂₉Cl₂N₃OS
• SMILES: Cl.CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl
• Target: Hedgehog/Smoothened,Smo
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.8 mM);DMSO:66 mg/mL (125.35 mM);Ethanol:38 mg/mL (72.17 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Hedgehog/Smoothened, Hedgehog, Smoothened Agonist HCl, Smoothened, SAG hydrochloride (912545 86 9(free base)), SAG hydrochloride (912545869(free base)), SAG hydrochloride (912545-86-9(free base))

Quick Database Links

Gene Symbol

Hedgehog/Smoothened,Smo