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Salmeterol xinafoate

SKU: orb1223547

Description

A long-acting beta2-adrenergic receptor agonist (Ki=1.5 nM) used clinically to treat asthma and maintenance of COPD. Asthma Approved(In Vitro):Salmeterol (0.001-25 μM) inhibits human T lymphocyte proliferation.(In Vivo):Salmeterol (0.16 mg/kg), Formoterol (0.32 mg/kg) and combined treatment have therapeutic effects in mice with chronic obstructive pulmonary disease (COPD).

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number94749-08-3
MW603.745
Purity>98% (HPLC)
FormulaC36H45NO7
SMILESC1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O.C1=CC=C2C(=C1)C=CC(=C2O)C(=O)O
TargetAdrenergic Receptor
SolubilityDMSO: ≥ 50 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GR-33343X xinafoate

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Salmeterol xinafoate (orb1223547)

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