Samelisant

SKU: orb1297886

Description

Samelisant (SUVN-G3031) is a potent, selective inverse agonist of the histamine H3 receptor, exhibiting Kis of 8.7 nM (human) and 9.8 nM (rat). It demonstrates anticataplectic activity in vivo and is a valuable research tool for investigating narcolepsy and related sleep/wake disorders in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1394808-82-2
• MW: 373.49
• Purity: 99.09% (May vary between batches)
• Formula: C₂₁H₃₁N₃O₃
• SMILES: O(C1CCN(CC1)C2CCC2)C3=CC=C(NC(CN4CCOCC4)=O)C=C3
• Target: Histamine Receptor
• Solubility: DMSO:50 mg/mL (133.87 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

H3 receptor, Histamine Receptor, HistamineReceptor, SUVN-G 3031, SUVN-G3031, SUVN-G-3031, Samelisant

Quick Database Links

Gene Symbol

Histamine Receptor