SB-202190

SKU: orb1305747

Description

SB 202190 is a potent, cell-permeable, and selective inhibitor of p38α and p38β2 MAP kinases. This compound is widely used in research to study inflammation, apoptosis, and cellular stress responses, and it has demonstrated utility in both in vitro models, such as stem cell differentiation into cardiomyocytes, and in vivo antitumor studies.

Research Area

Cell Biology, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 152121-30-7
• MW: 331.35
• Purity: >98%
• Formula: C₂₀H₁₄N₃OF
• SMILES: Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
• Target: Kinase
• Solubility: Soluble in DMSO (up to 30 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

p38α, p38β, p38MAPK, pocket, p38 MAPK, spatial, SB 202190, SB202190, SB-202190, deficits, colorectal, Autophagy, ATP, Apoptosis, anti-cancer, FHPI, Inhibitor, memory, learning, inhibit

Quick Database Links

Gene Symbol

Kinase