Seletalisib

SKU: orb1296248

Description

Seletalisib (UCB5857) is a highly selective PI3Kδ inhibitor with an IC50 of 12 nM. It is a valuable research tool for studying B-cell and immune cell signaling in vitro and has demonstrated efficacy in models of inflammatory and autoimmune diseases in vivo.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1362850-20-1
• MW: 482.85
• Purity: 95.87% (May vary between batches)
• Formula: C₂₃H₁₄ClF₃N₆O
• SMILES: [O-][n+]1cccc(c1)-c1nc2c(Cl)cccc2cc1[C@@H](Nc1ncnc2cccnc12)C(F)(F)F
• Target: PI3K
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (6.83 mM);DMSO:80 mg/mL (165.68 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, PI3K, PI3Kδ, Phosphoinositide 3-kinase, Seletalisib, UCB5857, UCB-5857, UCB 5857

Quick Database Links

Gene Symbol

PI3K