Simvastatin

SKU: orb1310385

Description

Simvastatin is an orally active HMG-CoA reductase inhibitor (Ki=0.2 nM) used in research to study cholesterol biosynthesis inhibition. It is applied in hypolipidemic, cardiovascular disease, and atherosclerosis research, utilizing both in vitro enzyme assays and in vivo animal models.

Research Area

Cell Biology

Key Properties

• CAS Number: 79902-63-9
• MW: 418.58
• Purity: >98%
• Formula: C₂₅H₃₈O₅
• SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
• Target: HMG-CoA reductase
• Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mevinolin

Quick Database Links

Gene Symbol

HMG-CoA reductase