Sitaxsentan sodium

SKU: orb1300569

Description

Sitaxsentan sodium (TBC11251 sodium salt) is a potent and highly selective endothelin A (ETA) receptor antagonist. It is a valuable research tool for investigating the role of endothelin-1 signaling in cardiovascular diseases, pulmonary hypertension, and cancer, both in cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 210421-74-2
• MW: 476.89
• Purity: ≥95% (May vary between batches)
• Formula: C₁₈H₁₄ClN₂O₆S₂·Na
• SMILES: [Na+].Cc1noc([N-]S(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl
• Target: Endothelin Receptor
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:60 mg/mL (125.82 mM);Ethanol:20 mg/mL (41.94 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.19 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IPI 1040, IPI-1040, IPI1040, inhibit, Inhibitor, Endothelin Receptor, EndothelinReceptor, ET-A, TBC11251 sodium, TBC11251 sodium salt, TBC-11251, TBC 11251, TBC11251, Thelin, Sitaxsentan sodium, Sitaxentan sodium, Sitaxsentan

Quick Database Links

Gene Symbol

Endothelin Receptor