Sobetirome

SKU: orb1301898

Description

Sobetirome (IACS-010759) is a selective thyroid hormone receptor beta (TRβ) agonist with an EC50 of 0.16 µM for TRβ-1. This compound is a research tool used in vitro and in vivo to study TRβ-mediated pathways in metabolism, lipid regulation, and related diseases.

Research Area

Metabolism Research

Key Properties

• CAS Number: 211110-63-3
• MW: 328.4
• Purity: 98.08% (May vary between batches)
• Formula: C₂₀H₂₄O₄
• SMILES: CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)ccc1O
• Target: Thyroid hormone receptor(THR)
• Solubility: Ethanol:30 mg/mL (91.35 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.09 mM);DMSO:145 mg/mL (441.53 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GC 1, GC1, GC-1, IACS 010759, IACS010759, IACS-010759, inhibit, Inhibitor, Sobetirome, TRβ, THR, QRX 431, QRX431, QRX-431, Thyroidhormonereceptor(THR), Thyroidhormonereceptor, Thyroid Hormone Receptor, Thyroid hormone receptor, Thyroid hormone receptor(THR)

Quick Database Links

Gene Symbol

Thyroid hormone receptor(THR)