Sodium dichloroacetate

SKU: orb1304008

Description

Sodium dichloroacetate (DCA) is a small molecule PDK inhibitor that shifts tumor cell metabolism from glycolysis to oxidative phosphorylation. This action reduces lactate, elevates ROS, and induces apoptosis, making it a valuable tool for studying cancer metabolism in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2156-56-1
• MW: 150.92
• Purity: 98.17% (May vary between batches)
• Formula: C₂HCl₂NaO₂
• SMILES: C(C(=O)[O-])(Cl)Cl.[Na+]
• Target: Apoptosis,Reactive Oxygen Species,PDK,Dehydrogenase,ROS,Na-K-Cl cotransporter
• Solubility: H2O:166.66 mg/mL (1104.29 mM);DMSO:26 mg/mL (172.28 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ReactiveOxygenSpecies, Reactive Oxygen Species, Sodium Dichloroacetate, Sodium bichloroacetic acid, Sodium dichloroacetate, Sodium dichloroacetate (DCA), dehydrogenase, DCA sodium salt, DCA, BCA, bichloroacetic acid, Apoptosis, NKCC, PDK, PDH kinase, PDH, PDHK, pyruvate, Pyruvate dehydrogenase kinase, mitochondria, lactic

Quick Database Links

Gene Symbol

Apoptosis,Reactive Oxygen Species,PDK,Dehydrogenase,ROS,Na-K-Cl cotransporter