Sodium Oxamate

SKU: orb1219607

Description

Sodium Oxamate is an LDH inhibitor. Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.It inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway.NETosis and lactate accumulation during LPS induced sepsis in mice was inhibited by sodium oxamate, LDH inhibitor.

Key Properties

• CAS Number: 565-73-1
• MW: 111.03
• Purity: >98% (HPLC)
• Formula: C₂H₂NNaO₃
• SMILES: [Na+].NC(=O)C([O-])=O
• Target: Apoptosis
• Solubility: In Vitro: H2O : 12.5 mg/mL (112.58 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SO, oxamate sodium, Aminooxoacetic acid sodium salt, Oxamic acid sodium salt

Quick Database Links

Gene Symbol

Apoptosis