Sorafenib tosylate

SKU: orb1310945

Description

Sorafenib tosylate is a multikinase inhibitor with potent activity against targets including Raf-1, VEGFR-3, and B-Raf (IC50s: 6, 20, 22 nM, respectively). It is widely used in preclinical research for investigating oncogenic signaling pathways and has demonstrated antitumor effects in both cellular assays and animal models of various cancers.

Research Area

Cell Biology

Key Properties

• CAS Number: 475207-59-1
• MW: 637.03
• Purity: 99.20% (May vary between batches)
• Formula: C₂₁H₁₆ClF₃N₄O₃·C₇H₈O₃S
• SMILES: Cc1ccc(cc1)S(O)(=O)=O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
• Target: Kinase
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:200 mg/mL (313.96 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.85 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BAY 43-9006

Quick Database Links

Gene Symbol

Kinase