SP-600125

SKU: orb1304531

Description

SP600125 is a potent, orally bioavailable, and reversible ATP-competitive inhibitor of JNK1, JNK2, and JNK3. It is widely used in research to study JNK signaling pathways, demonstrating effects on autophagy inhibition and apoptosis induction in both cellular and animal models of stress and disease.

Research Area

Cell Biology, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 129-56-6
• MW: 220.2
• Purity: >98%
• Formula: C₁₄H₈N₂O
• SMILES: O=C1C2=C3C(NN=C3C3=C1C=CC=C3)=CC=C2
• Target: Kinase
• Solubility: Soluble in DMSO (up to 22 mg/ml) or in Ethanol (up to 2 mg/ml).

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1,9-Pyrazoloanthrone

Quick Database Links

Gene Symbol

Kinase