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Spaglumic acid

SKU: orb1219508

Description

Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3106-85-2
MW304.26
Purity>98% (HPLC)
FormulaC11H16N2O8
SMILESCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TargetEndogenous Metabolite
SolubilityWater:29 mg/mL(95.31 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NAAG,N-Acetylaspartylglutamic acid

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Spaglumic acid (orb1219508)

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