Specnuezhenide

SKU: orb1303727

Description

Specnuezhenide (Nuezhenide) is a natural compound derived from Ligustrum lucidum fruit. It demonstrates anti-inflammatory activity by inhibiting NF-κB and Wnt/β-catenin signaling pathways, as shown in IL-1β-stimulated chondrocyte studies. This mechanism underlies its protective effects observed in rat models of osteoarthritis.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 39011-92-2
• MW: 686.66
• Purity: 98.00% (May vary between batches)
• Formula: C₃₁H₄₂O₁₇
• SMILES: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
• Target: NF-κB,Wnt/beta-catenin
• Solubility: DMSO:137.5 mg/mL (200.24 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.28 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Nuclear factor-kappaB, Nuclear factor-κB, Nuzhenide, Nuezhenide, NF-κB, NF-kB, NFkB, NFκB, bcatenin, anti-angiogenic, (8E)-Nuezhenide, diabetic retinopathy, betacatenin, beta-catenin, βcatenin, Wnt/β-catenin, Wnt/b-catenin, Wnt, Wnt/betacatenin, osteoarthritis, Specnuezhenide

Quick Database Links

Gene Symbol

NF-κB,Wnt/beta-catenin