SR1078

SKU: orb1302726

Description

SR1078 is a synthetic small molecule agonist that selectively activates the nuclear receptors RORα and RORγ. It is a valuable research tool for studying Th17 cell differentiation, cytokine production, and the role of these receptors in autoimmune and inflammatory diseases, as demonstrated in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 1246525-60-9
• MW: 431.3
• Purity: >98%
• Formula: C₁₇H₁₀F₉NO₂
• SMILES: OC(c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1)(C(F)(F)F)C(F)(F)F
• Target: Retinoid receptor and related
• Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SR 1078, SR1078, SR-1078, ROR, RORα, RORγ, RAR-related orphan receptor, Inhibitor, inhibit

Quick Database Links

Gene Symbol

Retinoid receptor and related