Stattic

SKU: orb1300882

Description

Stattic is a selective STAT3 inhibitor (IC50=5.1 µM) that blocks its activation, dimerization, and nuclear translocation. This compound exhibits antitumor and pro-apoptotic activity, making it a valuable research tool for studying STAT3 signaling in cancer models both in vitro and in vivo.

Research Area

Cell Biology

Key Properties

• CAS Number: 19983-44-9
• MW: 211.20
• Purity: >98%
• Formula: C₈H₅NO₄S
• SMILES: [O-][N+](=O)C1=CC=C2C=CS(=O)(=O)C2=C1
• Target: Transcription factor
• Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 1 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

prostate, Y705, SH2, P-ERK1/2, STAT, STAT3, Stattic, STAT3 Inhibitor V, syndrome, S727, S phase, p-STAT3, Inhibitor, inhibit, PC3M-1E8, cancer, Alport, Apoptosis

Quick Database Links

Gene Symbol

Transcription factor