STING agonist-4

SKU: orb1309057

Description

STING agonist-4 is a potent small molecule activator of the STING receptor, demonstrating an IC50 of 20 nM. It is widely used in immuno-oncology and antiviral research to stimulate the cGAS-STING pathway in both cellular assays and preclinical animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 2138300-40-8
• MW: 678.74
• Purity: 97.28% (May vary between batches)
• Formula: C₃₄H₃₈N₁₂O₄
• SMILES: CCn1nc(C)cc1C(=O)Nc1nc2cc(ccc2n1CCCCn1c(NC(=O)c2cc(C)nn2CC)nc2cc(ccc12)C(N)=O)C(N)=O
• Target: STING
• Solubility: DMSO:10 mg/mL (14.73 mM);H2O:< 0.1 mg/mL (insoluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MITA, MPYS, inhibit, ERIS, Inhibitor, STING agonist 4, STING agonist4, STING agonist-4, Stimulator of Interferon Genes, STING, TMEM173

Quick Database Links

Gene Symbol

STING