Sumatriptan succinate

SKU: orb1310839

Description

Sumatriptan succinate (GR 43175) is a selective 5-HT1 receptor agonist employed in migraine research. It is widely used in both in vitro binding assays and in vivo models to study its mechanism of vasoconstriction and neuronal inhibition for acute migraine relief.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 103628-48-4
• MW: 413.49
• Purity: 97.53% (May vary between batches)
• Formula: C₁₈H₂₇N₃O₆S
• SMILES: OC(=O)CCC(O)=O.CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1
• Target: 5-HT Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.84 mM);DMSO:55 mg/mL (133.01 mM);H2O:41.4 mg/mL (100.12 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antimigraine activity, 5-HT1D, 5-HT1B, 5-HT Receptor, 5-hydroxytryptamine Receptor, 5-HT, 5HT Receptor, 5HTReceptor, Inhibitor, inhibit, migraine headache, orally active, GR 43175, GR43175, GR-43175, Serotonin Receptor, Sumatriptan, Sumatriptan succinate, Sumatriptan Succinate

Quick Database Links

Gene Symbol

5-HT Receptor