Sunitinib Malate

SKU: orb1225255

Description

Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor. Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 341031-54-7
• MW: 532.56
• Purity: >98% (HPLC)
• Formula: C₂₆H₃₃FN₄O₇
• SMILES: CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C.C([C@@H](C(=O)O)O)C(=O)O
• Target: FGFR
• Solubility: DMSO: 15 mg/mL (28.16 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SU11248

Quick Database Links

Gene Symbol

FGFR