TABERSONINE HYDROCHLORIDE

SKU: orb1301470

Description

Tabersonine hydrochloride, a natural alkaloid derived from Voacanga africana, is a potent inhibitor of Aβ(1-42) aggregation and its associated cytotoxicity. This compound is utilized in Alzheimer's disease research for in vitro studies investigating amyloid-beta toxicity and potential neuroprotective mechanisms.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 29479-00-3
• MW: 372.89
• Purity: 98.17% (May vary between batches)
• Formula: C₂₁H₂₅ClN₂O₂
• SMILES: Cl.[H][C@@]12N3CC[C@]11C(Nc4ccccc14)=C(C[C@]2(CC)C=CC3)C(=O)OC
• Target: CDK,Akt,p38 MAPK,NOD-like Receptor (NLR),PI3K,NF-κB,Apoptosis,Cytochromes P450,Caspase,Beta Amyloid,Interleukin
• Solubility: H2O:3 mg/mL (8.05 mM);DMSO:50 mg/mL (134.09 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Beta Amyloid, BetaAmyloid, bAmyloid, b Amyloid, Aβ(1-42), Aβ, LI/ARDS, inhibit, Inhibitor, Tabersonine, TABERSONINE HYDROCHLORIDE, TABERSONINE Hydrochloride, βAmyloid, β Amyloid

Quick Database Links

Gene Symbol

CDK,Akt,p38 MAPK,NOD-like Receptor (NLR),PI3K,NF-κB,Apoptosis,Cytochromes P450,Caspase,Beta Amyloid,Interleukin