TARBP2 Antibody

SKU: orb248147

Description

TARBP2 (TAR (HIV-1) RNA binding protein 2), along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex). As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.

Images & Validation

• Tested Applications: WB
• Dilution Range: Western blot: 5-10ug/ml
• Reactivity: Human, Mouse, Primate
• Application Notes:
  Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment within the C-terminal region of TARBP2 was used as the immunogen for this antibody.
• Purification: Protein A Affinity Chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Western blot testing of human samples with TARBP2 antibody at 6 ug/ml.

N Shree, S Meruvu, MH Park, M Choudhury High-Fat-High-Fructose Diet Elicits Brown Adipocyte Dysfunction through miRNA-103 Induced miRNA Biogenesis Pathway Obesities, (2024)

Applications

WB

Reactivity

Mouse