Tauro-Obeticholic acid

SKU: orb1309028

Description

Tauro-Obeticholic acid is the active metabolite of the FXR agonist Obeticholic acid. It is used in research to study FXR-mediated pathways in metabolic and liver diseases, including in vitro assays and in vivo models of cholestasis and fibrosis.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 863239-61-6
• MW: 527.76
• Purity: 99.74% (May vary between batches)
• Formula: C₂₈H₄₉NO₆S
• SMILES: [H][C@@]12CC[C@H]([C@H](C)CCC(=O)NCCS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](O)[C@H](CC)[C@]2([H])C[C@H](O)CC[C@]12C
• Target: FXR
• Solubility: DMSO:50 mg/mL (94.74 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

colon, inhibit, NR1H4, ileum, metabolite,liver, microorganisms, Inhibitor, FXR, TauroObeticholic acid, Tauro-Obeticholic acid, Tauro Obeticholic acid

Quick Database Links

Gene Symbol

FXR