Tazobactam acid

SKU: orb1223720

Description

Tazobactam is a antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases.(In Vitro):Tazobactam (CL-298741) (5 μg/mL; 18 hours) has bactericidal activity and inhibit the growth of the bacteria in a dose-dependent manner.Tazobactam (CL-298741) (1-10 μg/mL; 6 hours; Prot. vulgaris and M. morgan) inhibits various types β-lactamase activity and with ID50 values of ＜ 10 μg/mL, respectively.(In Vivo):Tazobactam (CL-298741) (1000 mg/kg; i.p.; four times a day, for 36 and 84 hours; BALB/c mice) decreases the number of bacteria in mice and survived in low doses.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 89786-04-9
• MW: 300.29
• Purity: >98% (HPLC)
• Formula: C₁₀H₁₂N₄O₅S
• SMILES: C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
• Target: Antibiotic
• Solubility: DMSO: 10 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CL-298741 | YTR 830H

Quick Database Links

Gene Symbol

Antibiotic