Tegaserod maleate

SKU: orb1308220

Description

Tegaserod maleate (SDZ-HTF-919) is a selective 5-HT4 receptor agonist developed by Novartis. It was previously approved for IBS with constipation but was withdrawn due to cardiovascular risk concerns. This compound remains a valuable research tool for studying serotonergic pathways in gastrointestinal motility and related in vitro and in vivo models.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 189188-57-6
• MW: 417.46
• Purity: 98.00% (May vary between batches)
• Formula: C₂₀H₂₇N₅O₅
• SMILES: C(=C\C(O)=O)\C(O)=O.C(=NNC(NCCCCC)=N)C=1C=2C(NC1)=CC=C(OC)C2
• Target: Apoptosis,5-HT Receptor
• Solubility: DMSO:125 mg/mL (299.43 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.79 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-HT, 5HTReceptor, 5-hydroxytryptamine Receptor, 5HT Receptor, 5-HT Receptor, bowel, inhibit, irritable, SDZ-HTF 919, SDZ-HTF919, SDZ-HTF-919, HTF 919, HTF919, HTF-919, IBS, Inhibitor, Gastrointestinal, Serotonin Receptor, Sert (Sodium-dependent), syndrome, Tegaserod, Tegaserod maleate, Tegaserod Maleate

Quick Database Links

Gene Symbol

Apoptosis,5-HT Receptor