Tenofovir Disoproxil Fumarate

SKU: orb1305528

Description

Tenofovir Disoproxil Fumarate is the fumarate salt prodrug of tenofovir, an adenosine analog functioning as a nucleoside reverse transcriptase inhibitor. It is utilized in research for investigating antiviral mechanisms against HIV-1 and HBV in both cellular and animal models.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 202138-50-9
• MW: 635.51
• Purity: 98.60% (May vary between batches)
• Formula: C₁₉H₃₀N₅O₁₀P·C₄H₄O₄
• SMILES: OC(=O)\C=C\C(O)=O.CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc12)OCOC(=O)OC(C)C
• Target: Reverse Transcriptase,HBV,HIV Protease
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.15 mM);H2O:< 1 mg/mL (slightly soluble);Ethanol:44 mg/mL (69.24 mM);DMSO:50 mg/mL (78.68 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bis(POC)-PMPA, Hepatitis B virus, HBV, Inhibitor, Human immunodeficiency virus, HIVProtease, HIV Protease, HIV reverse transcriptase, HIV, GS4331, GS-4331, GS-1278 Disoproxil Fumarate, GS 4331, inhibit, Tenofovir Disoproxil, Tenofovir Disoproxil Fumarate, Tenofovir DF, ReverseTranscriptase, Reverse Transcriptase

Quick Database Links

Gene Symbol

Reverse Transcriptase,HBV,HIV Protease