Teriparatide acetate

SKU: orb1306346

Description

Teriparatide acetate (Forteo) is a recombinant parathyroid hormone (PTH) agonist with an IC50 of 2 nM in HEK293 cells. Its intermittent administration promotes osteoblast-mediated bone formation over resorption, making it a key anabolic therapy for osteoporosis and a valuable tool for bone metabolism research in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• Target: Thyroid hormone receptor(THR),Others
• CAS Number: 99294-94-7
• MW: 4177.83
• Purity: 99.67% (May vary between batches)
• Formula: C₁₈₃H₂₉₅N₅₅O₅₃S₂
• SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CNC=N2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC5=CNC=N5)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)N.CC(=O)O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cortical area, bone mineral content, parathyroid hormone, Parathar Acetate, Parathar acetate, osteoporosis, inhibit, Forteo, Inhibitor, hPTH (1-34) (acetate hydrate), hPTH 1-34, hPTH 1-34 (acetate salt), Teriparatide acetate, Teriparatide Acetate, PHT

Quick Database Links

Gene Symbol

Thyroid hormone receptor(THR),Others