Tetrandrine

SKU: orb1304758

Description

Tetrandrine is a natural bisbenzylisoquinoline alkaloid that acts as a calcium channel blocker, inhibiting both voltage-gated calcium channels and Ca2+-activated potassium channels. It is widely used in pharmacological research, including in vitro ion channel studies and in vivo models for investigating cardiovascular and anti-inflammatory pathways.

Research Area

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 518-34-3
• MW: 622.75
• Purity: 98.88% (May vary between batches)
• Formula: C₃₈H₄₂N₂O₆
• SMILES: O(C)C1=C2C=3[C@](CC=4C=C(C(OC)=CC4)OC=5C=CC(C[C@]6(C7=CC(O2)=C(OC)C=C7CCN6C)[H])=CC5)(N(C)CCC3C=C1OC)[H]
• Target: Parasite,Calcium Channel,Potassium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:0.7 mg/mL (1.12 mM);DMSO:12.45 mg/mL (19.99 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ca2+ channels, Calcium Channel, Ca channels, d-Tetrandrine, CalciumChannel, Inhibitor, Fanchinine, Hanfangchin A, KcsA, inhibit, NSC 77037, NSC77037, NSC-77037, Tetrandrine, Potassium Channel, PotassiumChannel, Sinomenine A

Quick Database Links

Gene Symbol

Parasite,Calcium Channel,Potassium Channel