TLR1

SKU: orb1308750

Description

TLR1 is a cell-permeable synthetic peptide that mimics the TIR domain/BB-loop, functioning as a potent inhibitor of IL-1 receptor signaling. This tool compound is widely used in vitro and in vivo to study inflammatory pathways, NLRP3 inflammasome activation, and interleukin-mediated immune responses.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 566914-00-9
• MW: 302.41
• Purity: 98.51% (May vary between batches)
• Formula: C₁₈H₂₆N₂O₂
• SMILES: C([C@@H](NC(CCC1=CC=CC=C1)=O)[C@@H](C)C)(=O)N2CCCC2
• Target: MyD88
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.61 mM);DMSO:30 mg/mL (99.2 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, MyD88, TLR 1, TLR-1, TLR1

Quick Database Links

Gene Symbol

MyD88