Tofacitinib Citrate

SKU: orb1305543

Description

Tofacitinib citrate is a potent and cell-permeable Janus kinase (JAK) inhibitor with selectivity for JAK1, JAK2, and JAK3. It is widely used in both in vitro and in vivo research to investigate JAK-STAT signaling pathways in immunology, inflammation, and autoimmune disease models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 540737-29-9
• MW: 504.49
• Purity: 99.19% (May vary between batches)
• Formula: C₂₂H₂₈N₆O₈
• SMILES: OC(=O)CC(O)(CC(O)=O)C(O)=O.C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N
• Target: Antibacterial,Influenza Virus,Antifungal,JAK,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.96 mM);DMSO:55 mg/mL (109.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tofacitinib, Tofacitinib (CP-690550) Citrate, Tofacitinib Citrate, Tasocitinib, Tasocitinib citrate, Tasocitinib Citrate, JAK1, JAK2, JAK, Janus kinase, JAK3, inhibit, InfluenzaVirus, Influenza Virus, Fungal, Inhibitor, CP690550, CP-690550, CP690550 Citrate, CP-690550 Citrate, CP-690550 citrate, CP 690550, CP 690550 Citrate, Apoptosis, Bacterial

Quick Database Links

Gene Symbol

Antibacterial,Influenza Virus,Antifungal,JAK,Apoptosis