eFT508

SKU: orb1304174

Description

Tomivosertib (eFT508) is a highly selective, potent dual inhibitor of MNK1 and MNK2 kinases, exhibiting IC50 values in the low nanomolar range. It is widely used in preclinical research to investigate MNK's role in oncogenesis and immune modulation, demonstrating antitumor activity in both cellular assays and in vivo animal models.

Research Area

Neuroscience

Key Properties

• CAS Number: 1849590-01-7
• MW: 340.4
• Purity: >98%
• Formula: C₁₇H₂₀N₆O₂
• SMILES: Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1
• Target: Kinase
• Solubility: Soluble in DMSO (2 mg/ml with warming)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tomivosertib

Quick Database Links

Gene Symbol

Kinase