Topotecan HCl

SKU: orb1309516

Description

Topotecan hydrochloride (NSC 609699) is a small molecule topoisomerase I inhibitor used as an antineoplastic agent. It is applied in ovarian cancer research and has been extensively studied in both in vitro cytotoxicity assays and in vivo xenograft models.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 119413-54-6
• MW: 457.9
• Purity: >98%
• Formula: C₂₃H₂₃N₃O₅ • HCl
• SMILES: Cl.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)c(CN(C)C)c4cc3Cn1c2=O
• Target: Topoisomerase
• Solubility: Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC 609669; SKF-104864A

Quick Database Links

Gene Symbol

Topoisomerase