TPA 023

SKU: orb1307656

Description

TPA 023 is a potent and selective agonist for GABAA receptors containing α2 and/or α3 subunits, exhibiting binding affinities in the sub-nanomolar range (Ki = 0.19 - 0.41 nM). This compound is a valuable research tool for investigating the roles of specific GABAA receptor subtypes in anxiety, sedation, and cognitive functions in both in vitro and in vivo studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 252977-51-8
• MW: 395.43
• Purity: 99.06% (May vary between batches)
• Formula: C₂₀H₂₂FN₇O
• SMILES: CCn1ncnc1COc1nn2c(nnc2cc1C(C)(C)C)-c1ccccc1F
• Target: GABA Receptor
• Solubility: DMSO:50 mg/mL (126.44 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GABA Receptor, GABAA, GABAReceptor, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, TPA 023, TPA023, TPA-023, γ-Aminobutyric acid Receptor

Quick Database Links

Gene Symbol

GABA Receptor