Treprostinil

SKU: orb1302048

Description

Treprostinil (Orenitram) is a potent agonist targeting the DP1, IP, and EP2 receptors with EC50 values of 0.6, 1.9, and 6.2 nM, respectively. It is widely used in research on pulmonary arterial hypertension, vascular biology, and related signaling pathways in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 81846-19-7
• MW: 390.51
• Purity: 99.29% (May vary between batches)
• Formula: C₂₃H₃₄O₅
• SMILES: CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@@H]2Cc3c(C[C@H]12)cccc3OCC(O)=O
• Target: Prostaglandin Receptor
• Solubility: Ethanol:20 mg/mL (51.22 mM);DMSO:150 mg/mL (384.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.12 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DP1, IP, Inhibitor, inhibit, LRX 15, LRX15, LRX-15, Orenitram, EP2, ProstaglandinReceptor, Prostaglandin Receptor, Remodulin, Treprostinil, UT 15, UT15, UT-15

Quick Database Links

Gene Symbol

Prostaglandin Receptor