trifarotene

SKU: orb1299684

Description

Trifarotene (CD5789) is a selective RARγ agonist, exhibiting 65-fold and 16-fold greater potency for RARγ (EC50=7.7 nM) over RARα and RARβ subtypes, respectively. This compound is a valuable research tool for studying retinoid signaling in models of dermatology and oncology, both in vitro and in vivo.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 895542-09-3
• MW: 459.58
• Purity: 99.51% (May vary between batches)
• Formula: C₂₉H₃₃NO₄
• SMILES: CC(C)(C)c1cc(ccc1N1CCCC1)-c1cc(ccc1OCCO)-c1ccc(cc1)C(O)=O
• Target: Retinoid Receptor,Autophagy
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.88 mM);DMSO:200 mg/mL (435.18 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, CD5789, CD-5789, CD 5789, Autophagy, acne, selective, RARγ, RAR, RAR/RXR, Retinoid X receptors, RetinoidReceptor, Retinoic acid receptors, Retinoid Receptor, trifarotene

Quick Database Links

Gene Symbol

Retinoid Receptor,Autophagy