Trilaciclib hydrochloride

SKU: orb1308992

Description

Trilaciclib hydrochloride (G1T28 hydrochloride) is a potent and selective CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. It is widely used in preclinical research to investigate cell cycle arrest, chemoprotection, and antitumor efficacy in both in vitro and in vivo cancer models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1977495-97-8
• MW: 519.47
• Purity: 98.61% (May vary between batches)
• Formula: C₂₄H₃₂Cl₂N₈O
• SMILES: Cl.Cl.CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1
• Target: CDK
• Solubility: DMSO:Insoluble;H2O:10 mM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclin dependent kinase, CDK, CDK4/Cyc D1, Cdk4/cyclin D1, cdk6/cyclin D3, CDK6/CyclinD3, Inhibitor, inhibit, G1T28, G1T28 Hydrochloride, G1T28 hydrochloride, Trilaciclib, Trilaciclib hydrochloride, Trilaciclib Hydrochloride

Quick Database Links

Gene Symbol

CDK