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U-73122

SKU: orb1300944

Description

U-73122 is a potent phospholipase C (PLC) inhibitor that suppresses agonist-triggered intracellular calcium mobilization in platelets and polymorphonuclear leukocytes (PMNs). It is widely used in vitro to study calcium signaling pathways in immunology, inflammation, and cardiovascular research.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number112648-68-7
MW464.7
Purity>98%
FormulaC29H40N2O3
SMILESCOc1ccc2[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CCc2c1)NCCCCCCN1C(=O)C=CC1=O
TargetPhospholipase
SolubilityVery soluble in Methylene chloride or Chloroform. Slightly soluble in DMSO (up to 2 mg/ml) or in Ethanol (up to 1 mg/ml).

Storage & Handling

StorageRT
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Phospholipase, U 73122, U73122, U-73122, PLC, LOX, inhibit, Lipoxygenase, Inhibitor, Ferroptosis

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Protocol Information

U-73122 (orb1300944)

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5 mg
$ 170.00
25 mg
$ 270.00
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