U0126-EtOH

SKU: orb1300964

Description

U0126-EtOH is a selective, non-ATP competitive inhibitor of MEK1 and MEK2. It is widely used in cell culture and animal studies to investigate MAPK/ERK signaling pathways, demonstrating utility in cancer research and studies of autophagy and mitophagy.

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 1173097-76-1
• MW: 426.6
• Purity: 98.65% (May vary between batches)
• Formula: C₁₈H₁₆N₆S₂·C₂H₆O
• SMILES: CCO.N\C(Sc1ccccc1N)=C(\C#N)/C(/C#N)=C(\N)Sc1ccccc1N
• Target: Influenza Virus,Mitophagy,Autophagy,MEK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:7.9 mg/mL (18.52 mM);DMSO:255 mg/mL (597.75 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, competitive, non-ATP, inhibit, InfluenzaVirus, Influenza Virus, Mitochondrial Autophagy, Mitophagy, Mitogen-activated protein kinase kinase, Inhibitor, MAP2K, MEK1, MEK2, MEK, MAPKK, progeny, virus, U-0126, U0126 Ethanol, U0126 EtOH, U0126EtOH, U-0126-EtOH, U0126-EtOH, U0126, U 0126

Quick Database Links

Gene Symbol

Influenza Virus,Mitophagy,Autophagy,MEK