Urolithin B

SKU: orb1219522

Description

Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.

Key Properties

• CAS Number: 1139-83-9
• MW: 212.2
• Purity: >98% (HPLC)
• Formula: C₁₃H₈O₃
• SMILES: Oc1ccc2c(c1)oc(=O)c1ccccc21
• Target: NF-κB
• Solubility: DMSO:249 mg/mL(1173.42 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB