Verteporfin

SKU: orb1304525

Description

Verteporfin is a clinically used photosensitizer and a small molecule inhibitor of the YAP-TEAD protein interaction, a key pathway in the Hippo signaling cascade. It has been widely utilized in research to study oncogenesis, fibrosis, and regenerative processes, demonstrating effects on apoptosis and autophagy in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 129497-78-5
• MW: 718.8
• Purity: >98%
• Formula: C₄₁H₄₂N₄O₈
• SMILES: COC(=O)CCc1c(C)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CCC(O)=O)c5C)[C@]1(C)[C@H](C(=O)OC)C(=CC=C41)C(=O)OC)c(C)c3C=C
• Target: Transcription factor
• Solubility: Soluble in DMSO (up to 14 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CL 318,952; BPD-MA

Quick Database Links

Gene Symbol

Transcription factor