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Vonafexor

SKU: orb1220251

Description

Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects.(In Vitro):Vonafexor (EYP001) inhibits the HBV replication cycle in HepaRG cells resulting in significant reductions in HBV DNA, HBsAg and HBeAg secretion, with additive effects when combined with Entecavir (HY-13623) or Tenofovir (HY-13910).

Images & Validation

Key Properties

CAS Number1192171-69-9
MW489.76
Purity>98% (HPLC)
FormulaC??H??Cl?N?O?S
SMILESO=C(C1=CC2=C(Cl)C(N3CCN(S(=O)(C4=C(Cl)C=CC=C4Cl)=O)CC3)=CC=C2O1)O
TargetFXR
SolubilityDMSO : 83.33 mg/mL (170.14 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

EYP001

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    98.74% (May vary between batches)

    1192171-69-9

    489.76

    C19H15Cl3N2O5S

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Vonafexor (orb1220251)

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