Voriconazole

SKU: orb1310918

Description

Voriconazole (UK-109496) is a triazole antifungal compound that acts as a potent inhibitor of fungal sterol 14-alpha-demethylase and the mammalian cytochrome P-450 CYP3A enzyme. It is widely used in research for studying antifungal mechanisms, drug interactions, and in both in vitro susceptibility testing and in vivo infection models.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 137234-62-9
• MW: 349.31
• Purity: 98.00% (May vary between batches)
• Formula: C₁₆H₁₄F₃N₅O
• SMILES: CC(C1=NC=NC=C1F)C(O)(CN1C=NC=N1)C1=CC=C(F)C=C1F
• Target: Antifection,Antifungal,Antibacterial
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.31 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:247 mg/mL (707.11 mM);Ethanol:16 mg/mL (45.8 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

14-α Demethylase, blastomycosis, broad-spectrum, antifungal, murine, inhibit, Inhibitor, Fungal, pulmonary, UK 109496, UK109496, UK-109496, Voriconazole, triazole

Quick Database Links

Gene Symbol

Antifection,Antifungal,Antibacterial