VR23

SKU: orb1300141

Description

VR23 is a potent and selective proteasome inhibitor, exhibiting nanomolar IC50 values against trypsin-like (1 nM) and chymotrypsin-like (50-100 nM) activities. Its distinct inhibitory profile makes it a valuable research tool for studying proteasome function in cellular and biochemical assays, including investigations into protein degradation pathways and related disease models.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 1624602-30-7
• MW: 477.88
• Purity: 98.99% (May vary between batches)
• Formula: C₁₉H₁₆ClN₅O₆S
• SMILES: [O-][N+](=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12
• Target: Caspase,Proteasome,Apoptosis
• Solubility: DMSO:29 mg/mL (60.68 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Chymotrypsin-like proteasomes, Caspase-like proteasomes, Apoptosis, Proteasome, Trypsin-like proteasomes, VR23, VR-23, VR 23

Quick Database Links

Gene Symbol

Caspase,Proteasome,Apoptosis