WS-12

SKU: orb1299839

Description

WS-12 is a high-potency, selective agonist of the TRPM8 ion channel, eliciting a robust cooling sensation with an EC50 of 193 nM. This small molecule is a valuable research tool for studying thermosensation, pain pathways, and channel pharmacology in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 68489-09-8
• MW: 289.41
• Purity: 99.71% (May vary between batches)
• Formula: C₁₈H₂₇NO₂
• SMILES: C(NC1=CC=C(OC)C=C1)(=O)[C@H]2[C@H]([C@H](C)C)CC[C@@H](C)C2
• Target: TRP/TRPV Channel
• Solubility: DMSO:50 mg/mL (172.77 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (8.64 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TRP Channel, TRPChannel, TRPM8, TRPV Channel, TRPVChannel, Transient receptor potential channels, WS12, WS-12, WS 12, HEK293T, Inhibitor, inhibit, cultured mouse DRG neurons, chronic neuropathic pain, AVX 012, AVX012, AVX-012, AR15512, AR-15512, AR 15512, analgesic effect

Quick Database Links

Gene Symbol

TRP/TRPV Channel