Y-33075 dihydrochloride

SKU: orb1308924

Description

Y-33075 dihydrochloride is a potent and selective ROCK inhibitor with an IC50 of 3.6 nM. This compound is a valuable research tool for investigating Rho-kinase signaling in cellular studies and has been utilized in preclinical models to explore cardiovascular and neurological pathways.

Research Area

Cell Biology, Epigenetics & Chromatin, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 173897-44-4
• MW: 353.25
• Purity: 98.88% (May vary between batches)
• Formula: C₁₆H₁₈Cl₂N₄O
• SMILES: Cl.Cl.C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
• Target: ROCK,PKC,CaMK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.32 mM);H2O:50 mg/mL (141.54 mM);DMSO:100 mg/mL (283.09 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CaMKII, inhibit, Inhibitor, Y 33075, Y 33075 Dihydrochloride, Y 33075 dihydrochloride, Rho-associated protein kinase, Rho-associated kinase, Rho-kinase, ROK, ROCK, PKC, Y33075 dihydrochloride, Y33075 Dihydrochloride, Y-33075, Y-33075 Dihydrochloride, Y33075

Quick Database Links

Gene Symbol

ROCK,PKC,CaMK