Zafirlukast

SKU: orb1300514

Description

Zafirlukast is a potent and selective antagonist of the leukotriene D4 receptor (IC50=0.6 µM). This orally active compound is used in asthma research for its anti-inflammatory properties and has been investigated in both in vitro binding assays and in vivo models of airway hyperresponsiveness.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 107753-78-6
• MW: 575.7
• Purity: >98%
• Formula: C₃₁H₃₃N₃O₆S
• SMILES: COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C
• Target: GPCR
• Solubility: Soluble in DMSO (up to 10 mg/ml).

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ICI-204219

Quick Database Links

Gene Symbol

GPCR