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ZK 756326

SKU: orb1223013

Description

ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

Images & Validation

Key Properties

CAS Number874911-96-3
MW429.38
Purity>98% (HPLC)
FormulaC21H28N2O3·2HCl
SMILESC1CN(CCN1CCOCCO)CC2=CC(=CC=C2)OC3=CC=CC=C3.Cl.Cl
TargetGPR

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • ZK 756326 [orb1304283]

    99.06% (May vary between batches)

    874911-96-3

    356.46

    C21H28N2O3

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ZK 756326 (orb1223013)

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