ZSTK474

SKU: orb1301016

Description

ZSTK474 is an orally bioavailable, ATP-competitive s-triazine derivative that selectively inhibits phosphatidylinositol 3-kinase (PI3K). This small molecule inhibitor is used in cancer research, demonstrating antitumor activity in both in vitro cellular assays and in vivo animal models of various malignancies.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 475110-96-4
• MW: 417.41
• Purity: >98%
• Formula: C₁₉H₂₁F₂N₇O₂
• SMILES: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
• Target: Kinase
• Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, Inhibitor, inhibit, PI3Kα, PI3Kγ, PI3Kβ, PI3Kδ, PI3K, Phosphoinositide 3-kinase, ZSTK-474, ZSTK 474, ZSTK474

Quick Database Links

Gene Symbol

Kinase